Substance, material.
A condition, subject or affair, especially one of concern.
An approximate amount or extent.
The essence; the pith; the embodiment.
Inducing cause or reason, especially of anything disagreeable or distressing.
Pus.
To be important.
(in negative constructions) To care about, to mind; to find important.
To form pus or matter, as an abscess; to maturate.